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canada goose black friday sale A pair canada goose jacket outlet toronto of research studies suggests progressive abnormalities in brain development can lead to schizophrenia in some individuals.The research, published in Biological Psychiatry, states that some individuals are susceptible to abnormal brain development because of genetic deficiencies.One paper studied individuals with a deletion of a small section of chromosome 22. This genetic deletion often results in the development of abnormalities in the structure of the heart and of the face, a condition called velocardiofacial syndrome (VCFS; also known as 22q11.2 deletion syndrome).Up to 32 percent of people with VCFS develop psychotic disorders including schizophrenia, which occurs in 1 percent of the general population.findings suggest that in VCFS, brain changes during mid adolescence, particularly in the temporal lobe, predict early signs of psychosis, saidKates. Suggests that it may be possible, eventually, to develop a screening tool that would identify those VCFS affected youth who are at the highest risk for schizophrenia.All of the young people were well at the beginning of the study, but some were at high genetic risk of developing schizophrenia due to having family members with schizophrenia.participants were examined repeatedly by a psychiatrist and with structural brain scans to see if there were changes in brain structure in people who later became unwell, explainedMcIntosh.the end of the study, we found that there were accelerated reductions in the volume of particular brain structures in the people at high risk, and additional reductions in the volume of the frontal lobes in those people who later developed schizophrenia. canada goose black friday sale

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